欧盟评估XAP 104 TPT作为育肥鸡等家禽饲料添加剂的安全性和有效性

 

　　经过评估，专家小组无法就添加剂XAP 104 TPT对目标物种、消费者和使用者的安全性得出结论。而该添加剂对育肥鸡是有效的，由于缺乏足够的数据，评估小组无法就添加剂对蛋鸡的功效得出结论。部分原文报道如下：

 

　　Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed （FEEDAP ） was asked to deliver a scientific opinion on the safety and efficacy of Axtra XAP 104 TPT as a zootechnical feed additive （digestibility enhancers） for poultry species. The additive contains three enzyme activities （endo‐1,4‐beta‐xylanase, protease and alpha‐amylase） produced by three different genetically modified strains. Viable cells and recombinant DNA of the strains producing the protease and amylase were not detected in the final product. Owing to the insufficient data, uncertainty remained on the presence in the additive of viable cells of the strain producing the xylanase. The results obtained in the genotoxicity and subchronic oral toxicity studies performed with the three fermentation products did not indicate safety concerns resulting from the fermentation products used in the formulation/manufacturing. However, uncertainties remain on the suitability of the test item used in the studies conducted with the xylanase; therefore, the Panel was not in the position to conclude on the toxicological potential of AXTRA  XAP 104 TPT . Consequently, the Panel could not conclude on the safety of the additive for the target species, consumers and users. Owing to the uncertainty on the presence of viable cells of one of the production strains in the additive, the Panel could not conclude on the safety for the environment. The FEEDAP Panel concluded that AXTRA  XAP 104 TPT is efficacious in chickens for fattening, chickens reared for laying and minor poultry species up to the point of lay at the level of 2,000 U xylanase, 200 U amylase and 4,000 U protease per kg feed. Owing to the lack of sufficient data, the Panel could not conclude on the efficacy of the additive for laying hens.

 

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