欧盟评估谷氨酸棒杆菌KCCM 80393生产的L-精氨酸作为所有动物饲料添加剂的安全性和有效性

 

　　经过评估，专家小组认为该添加剂对目标物种、消费者和环境是安全的。评估中的添加剂被认为是非反刍动物物种氨基酸L-精氨酸的有效来源。为了使补充的L-精氨酸对反刍动物和非反刍动物同样有效，需要防止其在瘤胃中降解。部分原文报道如下：

 

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-arginine produced with a genetically modified strain of Corynebacterium glutamicum (KCCM 80393) when used as a nutritional additive in feed and water for drinking for all animal species and categories. The Panel concluded that the product under assessment does not give rise to any safety concern with regard to the genetic modification of the production strain. No DNA of the production strain was detected in the final product. l-Arginine produced by fermentation with C. glutamicum KCCM 80393 is safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the target species. The FEEDAP Panel has concerns on the use of l-arginine in water for drinking. The use of l-arginine produced by fermentation with C. glutamicum KCCM 80393 in animal nutrition is considered safe for the consumers and for the environment. Regarding the user safety, in the absence of data, the FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and/or eyes, or to be a dermal or respiratory sensitiser. The additive l-arginine produced by fermentation with C. glutamicum KCCM 80393 is regarded as an efficacious source of the essential amino acid l-arginine for non-ruminant nutrition. For the supplemental l-arginine to be as efficacious in ruminants as in non-ruminant species, it requires protection against degradation in the rumen.

 

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