欧盟评估丁基羟基茴香醚对所有动物物种的安全性

　　食品伙伴网讯  2019年12月13日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就丁基羟基茴香醚（butylated hydroxy anisole ，BHA）对所有动物物种的安全性发表科学意见。

 

　　早在2018年，专家小组已就BHA的安全性和有效性发表了意见。经过评估，专家小组认为该物质添加量为150 mg BHA/kg全价饲料对所有动物物种是安全的。此次评估无法确定BHA在猫的全价饲料中的安全浓度。部分原文报道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed （FEEDAP） was asked to deliver a scientific opinion on the safety of butylated hydroxy anisole （BHA） for all animal species. In 2018, the Panel delivered an Opinion on the safety and efficacy of BHA. The Panel concluded that 'a weight of evidence of the limited data supports that 150 mg BHA/kg complete feed would be a safe dose for all animal species. However, a possible exception could be cat, with its known lower capacity for glucuronidation of phenolic compounds and for which no specific data were available'. The Applicant submitted a review of the metabolism of phenolic compounds in cats and an in vivo study with cats. No specific information on metabolic fate of BHA has been made available for the feline species. The lack of knowledge is of particular relevance considering the additional load of phenolic compounds by dietary BHA for the full lifetime expectancy of cats. Owing the shortcomings in the design and reporting, the in vivo study could not be used to conclude on the safety of BHA for cats. Consequently, the Panel reiterates that no safe concentration of BHA in complete feed for cats could be established.

 

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