欧盟评估一种谷氨酸棒杆菌生产的L-精氨酸作为所有动物物种添加剂的安全性和有效性

　　食品伙伴网讯  2019年5月2日，据欧盟食品安全局（EFSA）消息，应欧盟委员会的要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就转基因谷氨酸棒杆菌KCCM 80182发酵生产的L-精氨酸用做所有动物品种饲料和饮用水的营养添加剂发表科学意见。

 

　　部分原文报道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed （FEEDAP） was asked to deliver a scientific opinion on L‐arginine produced by fermentation with a genetically modified strain of Corynebacterium glutamicum KCCM 80182 when used as a nutritional additive in feed and water for drinking for all animal species categories. Viable cells of the production strain and its recombinant DNA were not detected in the additive. The product L‐arginine, manufactured by fermentation with C. glutamicum, KCCM 80182, does not give rise to any safety concern with regard to the production strain. L‐Arginine produced using C. glutamicum KCCM 80182 is considered safe for the target species. The FEEDAP Panel has concerns regarding the safety of the simultaneous oral administration of  L‐arginine via water for drinking and feed.L‐Arginine produced using C. glutamicum KCCM 80182 is safe for the consumer and for the environment. The additive is not hazardous by inhalation, is not a skin sensitiser, but is corrosive to skin and eyes. The product under assessment is considered an efficacious source of the amino acid l‐arginine for all animal species. For L‐arginine to be as efficacious in ruminants as in non‐ruminant species, it requires protection against microbial degradation in the rumen.

 

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