欧盟评估谷氨酸棒杆菌发酵产生的L-苏氨酸作为添加剂的安全性和有效性

　　食品伙伴网讯  2019年2月28日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组被要求就谷氨酸棒杆菌（Corynebacterium glutamicum）发酵产生的L-苏氨酸（L‐threonine）作为饲料和水中营养添加剂用于所有动物物种的安全性和有效性发布科学意见。

 

　　经过评估，FEEDAP研究小组认为，当添加适量时，谷氨酸棒状杆菌产生的L -苏氨酸作为添加剂对目标物种是安全的。

 

　　部分原文报道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed （FEEDAP） was asked to deliver a scientific opinion on l‐threonine produced by fermentation with Corynebacterium glutamicum ■■■■■ when used as a nutritional additive in feed and water for drinking for all animal species and categories. The product under assessment is l‐threonine produced by fermentation with a ■■■■■ strain of C. glutamicum （■■■■■）。 l‐Threonine produced by C. glutamicum ■■■■■ is considered safe for the target species when supplemented in appropriate amounts to the diet. The FEEDAP Panel has concerns on the safety of the simultaneous oral administration of l‐threonine via water for drinking and feed. l‐Threonine produced using C. glutamicum ■■■■■ is safe for the consumer. The additive is not a skin or eye irritant and is not a skin sensitiser. Although the workers can be exposed by inhalation, the results of an acute inhalation study showed that risk of adverse effects by inhalation is low. l‐Threonine produced using C. glutamicum ■■■■■ is safe for the environment. The product under assessment is considered an efficacious source of the amino acid l‐threonine for all animal species. For l‐threonine to be as efficacious in ruminants as in non‐ruminant species, it requires protection against degradation in the rumen.

 

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