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欧盟评估转基因米曲霉菌株 NZYM-AL生产的三酰甘油脂肪酶的安全性

放大字体  缩小字体 时间:2024-12-20 10:17 来源:食品伙伴网 作者: 泽夕    浏览:38  原文:
核心提示:2024年12月18日,欧盟食品安全局就一种食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性评价发布意见。
   食品伙伴网讯  2024年12月18日,欧盟食品安全局就一种食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性评价发布意见。
  
  据了解,这种食品酶是由转基因米曲霉菌株 NZYM-AL生产的,旨在用于4种食品生产过程。
  
  经过评估,专家小组得出结论,该食品酶在预期的使用条件下不会引起安全问题。部分原文报道如下:
  
  The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is produced with the genetically modified Aspergillus oryzae strain NZYM-AL by Novozymes A/S. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that, under the intended conditions of use, this food enzyme did not give rise to safety concerns. Due to the implementation of a new methodology to estimate the dietary exposure to food enzymes in 2016, the European Commission requested EFSA to revise the exposure assessment of this food enzyme by using this new methodology. In this assessment, EFSA realigned the intended uses of this food enzyme to four food manufacturing processes. The dietary exposure was calculated to be up to 0.089 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (49.1 mg TOS/kg bw per day, the lowest dose tested), the Panel derived a margin of exposure of at least 552. based on the revised exposure estimate, the margin of exposure calculated thereof and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
  
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日期:2024-12-20
 

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