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欧盟评估扩展使用非转基因黑曲霉菌株AE-TGU生产的α-葡萄糖苷酶的安全性

放大字体  缩小字体 时间:2024-04-12 16:30 来源:食品伙伴网 作者: 泽夕    浏览:177  原文:
核心提示:2024年4月10日,欧盟食品安全局就一种食品酶α-葡萄糖苷酶(α-glucosidase)的安全性评价发布意见。
   食品伙伴网讯  2024年4月10日,欧盟食品安全局就一种食品酶α-葡萄糖苷酶(α-glucosidase)的安全性评价发布意见。
 
  据了解,这种食品酶是由非转基因黑曲霉菌株AE-TGU生产的,旨在用于七种食品生产过程。
 
  经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme α-glucosidase (α-d-glucoside glucohydrolase; EC 3.2.1.20) is produced with the non-genetically modified Aspergillus niger strain AE-TGU by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in four food manufacturing processes. Subsequently, the applicant requested to extend its use to include three additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of seven food manufacturing processes. The dietary exposure to the food enzyme-total organic solids (TOS) was estimated to be up to 0.693 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1062 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 1532. based on the data provided for the previous evaluation and the revised margin of exposure, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
 
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日期:2024-04-12
 

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