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欧盟评估LNFP-I/2’-FL混合物作为新型食品的安全性

放大字体  缩小字体 时间:2023-12-05 09:53 来源:食品伙伴网 作者: 泽夕    浏览:94  原文:
核心提示:2023年12月1日,据欧盟食品安全局(EFSA)消息,欧盟营养、新型食品和食物过敏源(NDA)研究小组就乳酰-N-岩藻五糖I/2′-岩藻糖基乳糖(LNFP-I/2’-FL)混合物作为新型食品的安全性发表科学意见。
   食品伙伴网讯  2023年12月1日,据欧盟食品安全局(EFSA)消息,欧盟营养、新型食品和食物过敏源(NDA)研究小组就乳酰-N-岩藻五糖I/2′-岩藻糖基乳糖(LNFP-I/2’-FL)混合物作为新型食品的安全性发表科学意见。
 
  经过评估,专家小组得出结论,在提议的使用条件下,LNFP-I/2’-FL混合物作为新型食品是安全的。部分原文报道如下:
 
  Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on lacto-N-fucopentaose I (LNFP-I)/2′-fucosyllactose (2’-FL) mixture as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human-identical milk oligosaccharides (HiMO) LNFP-I and 2’-FL, but it also contains d-lactose, lacto-N-tetraose, difucosyllactose, 3-fucosyllactose, LNFP-I fructose isomer, 2′-fucosyl-d-lactulose, l-fucose and 2′-fucosyl-d-lactitol, and a small fraction of other related saccharides. The NF is produced by fermentation by a genetically modified strain (Escherichia coli K-12 DH1 MDO MP2173b) of E. coli K-12 DH1 (DSM 4235). The information provided on the identity, manufacturing process, composition and specifications of the NF does not raise safety concerns. The applicant intends to add the NF in a variety of foods, including infant formula (IF) and follow-on formula, foods for infants and toddlers, foods for special medical purposes and food supplements (FS). The target population is the general population. The anticipated daily intake of LNFP-I from use in IF is similar to the estimated natural mean highest daily intake in breastfed infants. Overall, the anticipated daily intake of LNFP-I from the NF as a food ingredient at the maximum proposed use levels is unlikely to exceed the intake level of breastfed infants on a body weight basis. The intake in breastfed infants on a body weight basis is expected to be safe also for other population groups. The anticipated 2’-FL intake is generally rather low. The use of the NF in FS is not intended if other foods with added NF components or human milk (for infants and young children) are consumed on the same day. The Panel concludes that the NF, a mixture of LNFP-I and 2’-FL, is safe under the proposed conditions of use.
 
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日期:2023-12-05
 

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