欧盟评估大肠杆菌CGMCC 7.398生产的L-赖氨酸硫酸盐作为所有动物饲料添加剂的安全性和有效性

 

　　经过评估，专家小组认为在拟议的使用条件下，该添加剂对目标物种、消费者和环境是安全的。评估中的添加剂被认为是非反刍动物物种氨基酸L-赖氨酸的有效来源。为了使补充的L-赖氨酸对反刍动物和非反刍动物同样有效，需要防止其在瘤胃中降解。部分原文报道如下：

 

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-lysine sulfate produced by the genetically modified strain Escherichia coli CGMCC 7.398 as a nutritional feed additive for all animal species. Neither the production strain nor its recombinant DNA were detected in the final product. The additive does not pose any safety concerns associated with the production strain. The additive under assessment is considered safe for the target species. When using l-lysine sulfate, the background sulfur/sulfate content in the compound feed should be taken into account. l-lysine sulfate produced by E. coli CGMCC 7.398 is safe for the consumers and for the environment. In the absence of data, the FEEDAP Panel cannot conclude on the potential of the additive under assessment to be irritant to skin or eyes, or on its potential to be a dermal sensitiser. The endotoxin activity of the additive represents a risk by inhalation for users handling the additive. The additive l-lysine sulfate is considered as an efficacious source of the essential amino acid l-lysine for non-ruminant animal species. For the supplemental l-lysine to be as efficacious in ruminants as it is in non-ruminant species, this would require protection against degradation in the rumen.

 

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