欧盟评估一种L-赖氨酸浓缩液体和L-赖氨酸盐酸盐作为所有动物饲料添加剂的安全性和有效性

 

　　据条例，这种L-赖氨酸浓缩液体和L-赖氨酸盐酸盐由谷氨酸棒杆菌KCCM 80216发酵产生。经过评估，专家小组认为该添加剂对所有动物物种、消费者和环境是安全的。L-赖氨酸浓缩液体和L-赖氨酸盐酸盐被认为是非反刍动物物种必需氨基酸L-赖氨酸的有效来源。为了使补充的赖氨酸对反刍动物和非反刍动物同样有效，需要防止其在瘤胃中降解。部分原文报道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of concentrated liquid l‐lysine (base, minimum 50%) and l‐lysine monohydrochloride (HCl, minimum 99%) produced by fermentation with a genetically modified strain of Corynebacterium glutamicum (KCCM 80216) as nutritional additives for all animal species. Neither the production strain nor its recombinant DNA was detected in the final products. The additives do not pose any safety concern associated with the genetic modification of the production strain. Concentrated liquid l‐lysine (base) and l‐lysine HCl produced by C. glutamicumKCCM 80216 do not represent a risk for the target species, the consumer and the environment. From the results of studies on the safety for the user of concentrated liquid l‐lysine (base) and l‐lysine HCl produced by a different production strain, it was possible to conclude on the safety for the user of the products under assessment. The concentrated liquid l‐lysine (base) and the l‐lysine HCl are not irritant to skin or eyes or skin sensitiser. l‐lysine HCl is not hazardous by inhalation. l‐lysine HCl and concentrated liquid l‐lysine (base) are considered as efficacious sources of the essential amino acid l‐lysine for non‐ruminant animal species. For the supplemental l‐lysine to be as efficacious in ruminants as in non‐ruminant species, it would require protection against degradation in the rumen.

 

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