欧盟评估一种磷脂酶A2的安全性

 

　　据了解，这种食品酶是由AB Enzymes GmbH公司用转基因里氏木霉（Trichoderma reesei）菌株 RF8793生产的，旨在用于油脂的脱胶和鸡蛋改性卵磷脂的生产中。

 

　　经过评估，专家小组认为，在预期的使用条件下，不能排除通过饮食接触引起过敏和诱发反应的风险，但可能性被认为很低。由于TOS值是毒理学和暴露评估的基础，因此专家小组无法对转基因里氏木霉菌株RF8793产生的食品酶磷脂酶A2进行评估。部分原文报道如下：

 

　　The food enzyme phospholipase A2 (phosphatidylcholine 2‐acylhydrolase) is produced with the genetically modified Trichoderma reesei strain RF8793 by AB Enzymes GmbH. The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable cells of the production organism and its DNA. The food enzyme is intended to be used in degumming of fats and oils and modified lecithin production from egg. Due to lack of data on the compositional parameters, total organic solids (TOS) values could not be calculated. For this reason, the representativeness of the batch used for toxicological examination could not be established and dietary exposure could not be calculated. The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood is considered to be low. As TOS values form the basis of toxicological and exposure assessments, the Panel is not in a position to conclude its assessment of the food enzyme phospholipase A2 produced with the genetically modified Trichoderma reesei strain RF8793.?

 

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