欧盟评估L-赖氨酸硫酸盐作为所有动物饲料添加剂的安全性和有效性

 

　　据了解，L-赖氨酸硫酸盐是由谷氨酸棒杆菌 KFCC 11043经发酵制成的添加剂。经过评估，专家小组认为该添加剂对目标物种、消费者和环境是安全的。L-赖氨酸硫酸盐被认为是非反刍动物物种必需氨基酸L-赖氨酸的有效来源，为了使补充的L-赖氨酸对反刍动物和非反刍动物一样有效，需要防止其在瘤胃中降解。部分原文报道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed （FEEDAP ） was asked to deliver a scientific opinion on l ‐lysine sulfate produced by fermentation using Corynebacterium glutamicum KFCC 11043 when used as a nutritional additive in feed for all animal species. The active substance is l ‐lysine. The production strain qualifies for the qualified presumption of safety （QPS ） approach to safety assessment and was not detected in the final product. l ‐Lysine sulfate produced using C. glutamicum KFCC 11043 does not pose any safety concern associated with the production strain. l ‐Lysine sulfate produced by C. glutamicum KFCC 11043 is considered safe for the target species. When using l ‐lysine sulfate, the background sulfur/sulfate content in the compound feed should be taken into account. l ‐Lysine sulfate produced by C. glutamicum KFCC 11043 is safe for the consumer and for the environment. From the results of studies on the safety for the user of l ‐lysine sulfate produced by a different production strain, it was possible to conclude on the safety for the user of the product under assessment. l ‐Lysine sulfate produced by C. glutamicum KFCC 11043 is considered non‐toxic by inhalation, non‐irritant to skin or eyes and it is not a skin sensitiser. l ‐lysine sulfate is considered as an efficacious source of the essential amino acid l ‐lysine for non‐ruminant animal species. For the supplemental l ‐lysine to be as efficacious in ruminants as in non‐ruminant species, it would require protection against degradation in the rumen.

 

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