欧盟评估伏马菌素酯酶作为所有动物饲料添加剂的安全性和有效性

 

　　据了解，伏马菌素酯酶是由Komagataella phaffii DSM 32159制成的添加剂，旨在降解饲料污染物中的伏马菌素霉菌毒素。经过评估，专家小组认为在建议的使用条件下该添加剂对目标物种、消费者和环境是安全的。当以最低建议剂量40 U / kg饲料使用时，该添加剂具有降解发酵饲料中的伏马毒素的能力（伏马毒素的含量在欧盟规定的指导范围内）。专家小组指出，仅在青贮饲料中才显示出功效，而在其他发酵饲料（如液体饲料）中却没有显示出这种功效。部分原文报道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed （FEEDAP ） was asked to deliver a scientific opinion on the safety and efficacy of fumonisin esterase from Komagataella phaffii DSM 32159 as a technological feed additive for all animal species. The product has been already assessed by the FEEDAP Panel for use in pigs and poultry feed as technological additive and was granted with an authorisation in the EU for this use. In the current application, the additive is intended to be used in fermenting feeds with the purpose to reduce the contamination of feed by fumonisins. New data provided showed that no recombinant DNA could be detected in three batches of the product. The evidence provided – based on the data submitted in the previous and the current application – allowed the FEEDAP Panel to conclude that the additive is safe for the target animals under the proposed conditions of use. The Panel also considered valid the previous conclusions in which the safety of the additive for consumers and the environment was established. The additive is not toxic by inhalation and the respiratory exposure is likely to be low; however, a risk of sensitisation via the respiratory route cannot be excluded. The additive is non‐irritant to skin and eyes and is not considered as a dermal sensitiser. The additive has the capacity to degrade fumonisins in fermenting feed （with a fumonisin content within the guidance limits operating in the EU ） when used at the minimum recommended dose of 40 U/kg feed. The FEEDAP Panel notes that the efficacy has been demonstrated only in silages, not in other fermenting feeds like e.g. liquid feeds.

 

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