欧盟评估一种6-植酸酶制剂的安全性和有效性　　

　　食品伙伴网讯   2020年5月29日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就PHYTAFEED（6-植酸酶（6-phytase））作为蛋鸡和其他产蛋家禽饲料添加剂的安全性和有效性发表科学意见。

 

　　据了解，该添加剂是一种6-植酸酶制剂，由一种转基因巴斯德毕赤酵母（Komagataella phaffii）产生。经过评估，专家小组认为该添加剂对目标物种、消费者和环境是安全的，在使用水平为300 U/kg饲料时，可能对目标物种有效。部分原文报道如下：

 

　　Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed （FEEDAP ） was asked to deliver a scientific opinion on the safety and efficacy of APSA PHYTAFEED ? 20,000 GR /L （6‐phytase） as a zootechnical feed additive for laying hens and other poultry species for laying. The additive is a preparation of 6‐phytase produced by a genetically modified strain of Komagataella phaffii and has been previously assessed by the FEEDAP Panel in the context of three applications for its use in different species/categories. The Panel concluded in those opinions that the production strain is safe, and that the use of the additive as a feed additive would raise no safety concerns for the consumers and the environment. The additive was also considered not to be irritant to skin or eyes or a dermal sensitiser but it should be considered as a respiratory sensitiser. The Panel considered that the new use in laying hens and other poultry species for laying would not modify the previously drawn conclusions with respect to the consumers, users and the environment. A tolerance trial in laying hens and a subchronic oral toxicity study were made available to support the safety of the additive for the target species/categories subject of this new application; from the results obtained, the Panel concluded that the additive is safe for laying hens at the recommended level of use （300 U/kg feed） with a wide margin of safety and therefore the conclusion was extrapolated to other laying birds.

 

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