欧盟评估一种6-植酸酶制剂作为饲料添加剂的安全性和有效性

　　食品伙伴网讯  2020年1月16日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就PHYTAFEED® 20000 GR/L（6-植酸酶（6-phytase））作为猪育肥饲料添加剂的安全性和有效性发表科学意见。

 

　　据了解，该添加剂是一种6-植酸酶制剂，其中6-植酸酶由一种转基因巴斯德毕赤酵母（Komagataella phaffii） 菌株产生。经过评估，FEEDAP小组得出结论认为，此种添加剂不会给消费者和环境带来安全问题，在1000 U/kg饲料的使用水平下对目标物种是安全的，但无法得出其有效性。

 

　　部分原文报道如下：

 

　　Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed （FEEDAP） was asked to deliver a scientific opinion on the safety and efficacy of APSA PHYTAFEED® 20,000 GR/L （6‐phytase） as a feed additive for pigs for fattening. The additive is a preparation of 6‐phytase produced by a genetically modified strain of Komagataella phaffii and has been previously assessed by the FEEDAP Panel in the context of three applications for its use in different species. The Panel concluded in those opinions that the production strain is safe, and that the use of the additive as a feed additive would raise no safety concerns for the consumers and the environment. The additive was also considered not to be irritant to skin or eyes or a dermal sensitiser but it should be considered as a respiratory sensitiser. The Panel considered that the new use in pigs for fattening would not modify the previously drawn conclusions with respect to the consumers, users and the environment. A tolerance trial in weaned piglets and a subchronic oral toxicity study were made available to support the safety for the new target species.

 

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