欧盟评估大肠杆菌CGMCC 7.232发酵产生的L-苏氨酸的安全性和有效性

    食品伙伴网讯  2018年10月25日，欧盟食品安全局（EFSA）就大肠杆菌CGMCC 7.232发酵产生的L-苏氨酸对所有动物的安全性和有效性发布意见。

 

    由大肠杆菌基因修饰菌株（ CGMCC 7.232 ）发酵产生的L-苏氨用于所有动物物种的饲料和饮用水，在生产菌株的基因改造方面没有引起任何安全问题，对用于特定物种以及消费者也是安全的。但在没有数据的情况下，欧盟食品安全局动物饲料专家组（FEEDAP）无法断定添加剂对皮肤和眼睛有刺激性或是皮肤致敏的可能性。对于处理添加剂的人来说，有吸入接触内毒素的风险。

 

    部分原文报道如下：

 

    The product subject of this assessment is l‐threonine produced by fermentation with a genetically modified strain of Escherichia coli （CGMCC 7.232）。 It is intended to be used in feed and water for drinking for all animal species and categories. The production strain and its recombinant DNA were not detected in the additive. The product l‐threonine, manufactured by fermentation with E. coli CGMCC 7.232, does not raise any safety concern with regard to the genetic modification of the production strain. l‐Threonine produced using E. coli CGMCC 7.232 is considered safe for the target species. The FEEDAP Panel has concerns regarding the safety of the simultaneous administration of l‐threonine via water for drinking and feed. l‐Threonine produced using E. coli CGMCC 7.232 is safe for the consumer. In absence of data, the FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and eyes or to be a skin sensitiser. There is a risk from the inhalation exposure to endotoxins for persons handling the additive. l‐Threonine produced using E. coli CGMCC 7.232 is safe for the environment. The product under assessment is considered an efficacious source of the amino acid l‐threonine for all animal species. For l‐threonine to be as efficacious in ruminants as in non‐ruminant species, it requires protection against degradation in the rumen.

 

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