欧盟评估河豚毒素及其类似物的公共健康风险

 

    欧盟专家组审查了现有的文献认为，无足够证据支持河豚毒素最小致死剂量为2毫克的结论，部分人摄取仅0.2毫克，相当于4微克/千克体重，即可出现严重症状。

 

    经过风险评估，欧盟食品安全局认为，贝肉浓度低于44微克当量TTX / kg不会对人体产生不利影响。液相色谱串联质谱法（LC-MS / MS）最适合检测河豚毒素及其类似物，定量限为0.1-25微克/千克。

 

    部分原文报道如下：

 

    Tetrodotoxin （TTX） and its analog ues are produced by marine bacteria and have been dete cted inmarine bivalves and gastropods from European waters. The European Commission asked EFSA for ascienti?c opinion on the risks to public health related to the presence of TTX and TTX analogues inmarine bivalves and gastropods. The Panel on Contaminants in the Food Chain reviewed the availableliterature but did not ?nd support for the minimum lethal dose for humans of 2 mg, mentioned invarious reviews. Some human case reports describe serious effects at a dose of 0.2 mg, correspondingto 4 lg/kg body weight （bw）。