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欧盟评估转基因黑曲霉菌株XEA生产的内切-1,4-β-木聚糖酶的安全性

放大字体  缩小字体 时间:2025-03-31 10:43 来源:食品伙伴网 作者: 泽夕    浏览:90  原文:
核心提示:2025年3月28日,欧盟食品安全局就一种食品酶内切-1,4-β-木聚糖酶(endo-1,4-β-xylanase)的安全性评价发布意见。
   食品伙伴网讯  2025年3月28日,欧盟食品安全局就一种食品酶内切-1,4-β-木聚糖酶(endo-1,4-β-xylanase)的安全性评价发布意见。
 
  据了解,这种食品酶是由转基因黑曲霉菌株XEA生产的,旨在用于6种食品制造过程。
 
  根据新的数据、修订的暴露限度和以前的评估,小组得出结论,该食品酶在预期的使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme endo-1,4-β-xylanase (4-β-d-xylan xylanohydrolase, EC 3.2.1.8) is produced with the genetically modified Aspergillus niger strain XEA by DSM Food Specialties B.V. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in two food manufacturing processes. Subsequently, the applicant has requested to extend its use to include four additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of six food manufacturing processes. The dietary exposure was calculated to be up to 0.316 mg total organic solids (TOS)/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1852 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 5861. based on the new data, the revised margin of exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
 
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日期:2025-03-31
 

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