热门搜索:
 
当前位置: 首页 » 信息动态 » 正文

欧盟重新评估与脂肪酸一甘油酯氧化的大豆油和与脂肪酸二甘油酯氧化的大豆油作为食品添加剂的安全性

放大字体  缩小字体 时间:2018-10-11 15:41 来源:食品伙伴网 作者:  浏览:276  原文:
核心提示:2018年10月10日,欧盟食品安全局(EFSA)发布与脂肪酸一甘油酯氧化的大豆油和与脂肪酸二甘油酯氧化的大豆油(E479b)作为食品添加剂安全性的评估结果。
    食品伙伴网讯  2018年10月10日,欧盟食品安全局(EFSA)发布与脂肪酸一甘油酯氧化的大豆油和与脂肪酸二甘油酯氧化的大豆油(E479b)作为食品添加剂安全性的评估结果。
 
    欧盟食品添加剂和调味剂小组( FAF )经过评估后,认为现有的毒理学数据不足以支持目前需要进行ADME和发育毒理学研究的每日容许摄入量(ADI)。
 
    部分原文报道如下:
 
    The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion re‐evaluating the safety of thermally oxidised soya bean oil interacted with mono‐ and diglycerides of fatty acids (TOSOM) (E 479b) when used as a food additive. The Scientific Committee on Food (SCF) and the Joint FAO/WHO Expert Committee on Food Additives (JECFA) derived an acceptable daily intake (ADI) of 25 and 30 mg/kg body weight (bw) per day, respectively. There was no reliable information regarding the absorption, distribution, metabolism, excretion (ADME) for TOSOM. No adverse effects have been detected in a limited subchronic toxicity study in pigs. The Panel identified a no observed adverse effect level (NOAEL) of 5,400, the highest dose tested, from a chronic and carcinogenicity study in rats. No genotoxicity data were available. No reliable studies for reproductive or developmental toxicity were available. From the chronic and carcinogenicity study, no lesions in reproductive organs were described and the lack of carcinogenic effect alleviated the concern for genotoxicity at the first site of contact. The Panel concluded that the available toxicological data were insufficient to support the current ADI, in particular, due to the lack of ADME data and absence of developmental toxicity studies TOSOM (E 479b) is only authorised in one food category and only one reported use level that equals the maximum permitted level was submitted.
 
    本文由食品伙伴网食品资讯中心编辑,供网友参考,欢迎转载,转载请注明出处!有任何疑问,请联系news@foodmate.net。

本文由食品伙伴网编译,供网友参考,食品伙伴网提供欧盟、美国、英国、俄罗斯、日本、韩国、东南亚、西班牙等国家或地区的进出口合规咨询服务,欢迎垂询:0535-2129301,Email:vip@foodmate.net、news@foodmate.net.

日期:2018-10-11
 

声明:

本网转载内容均已注明出处,转载目的在于传递更多信息,并不代表本网赞同其观点和对其真实性负责。
※ 如果有侵权或其他问题,请联系电话:0535-2122172

 
[ 信息动态搜索 ]  [ 告诉好友 ]  [ 打印本文 ]  [ 关闭窗口 ]

 

 
行业相关食品资讯
 
地区相关食品资讯