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欧盟发布维生素E作为饲料添加剂的安全性和有效性的科学意见

放大字体  缩小字体 时间:2010-06-17 08:29 来源:欧盟食品安全局  浏览:615  原文:
核心提示:欧盟发布维生素E作为饲料添加剂的安全性和有效性的科学意见
    食品伙伴网导读:2010年6月15日,欧盟发布维生素E作为饲料添加剂的安全性和有效性的科学意见。

    原文报道:

The full opinion will be published in accordance with Article 8(6) of Regulation (EC) No 1831/2003 once the decision on confidentiality, in line with Article 18(2) of the Regulation, will be received from the European Commission.

Summary

Following a request from European Commission, the European Food Safety Authority was asked to deliver a scientific opinion on the safety and efficacy of vitamin E as a feed additive for all animal species.

Vitamin E is a well-established micro-nutrient for all animal species. Vitamin E-based additives are globally used in animal nutrition, and have been for decades, to prevent vitamin E deficiency.

The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) examined data from three active substances (all-rac-α-tocopheryl acetate, RRR-α-tocopheryl acetate and RRR-α-tocopherol) currently authorised as vitamin E. The biopotency of these forms is different: one International Unit (IU) of vitamin E is defined as 1 mg all-rac-α-tocopheryl acetate, as 0.74 mg of RRR-α-tocopheryl acetate and as 0.67 mg of RRR-α-tocopherol.

The additives described containing those forms of vitamin E do not present major stability or homogeneity issues. However, sensitivity to light and moisture, as well as to oxygen and heat for RRR-preparations, must be appropriately managed in order to maintain the amount of vitamin E nominally available to farm animals.

Vitamin E at the current use levels is safe for all animal species. Information on hypervitaminosis E is not sufficiently consistent to derive a maximum content for vitamin E in feedingstuffs, based on safety for target species.

A conservative consumer exposure assessment indicates that the UL (300 mg α-tocopherol equivalents/day) is not exceeded even assuming high background intake and levels in animal feeds far higher than practical use. The FEEDAP Panel concludes that the use of vitamin E at practical use levels is safe for the consumer.

No concern for user safety is expected from the use of the active substances vitamin E in feed additives. However, to draw conclusions on the final formulated additives, specific studies would be required.

Vitamin E occurs in nature and its use in animal nutrition will not result in a substantial increase in concentration in the environment. Therefore, no concern for the environment is expected.

All-rac-α-tocopheryl acetate, RRR-α-tocopherol and RRR-α-tocopheryl acetate are efficacious in all animal species in satisfying the requirements for vitamin E.

The FEEDAP Panel makes specific recommendations concerning (i) labelling of vitamin E in IU, (ii) restricting the use of oily RRR-α-tocopherol to premixture manufacturers, (iii) the introduction of a recommended maximum of 200 IU vitamin E/kg complete feedingstuffs, (iv) the specification of the additives.

    详情见:http://www.efsa.europa.eu/en/scdocs/scdoc/1635.htm 

日期:2010-06-17
 

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